While Galvanic current has been available for over 50 years, a licensed esthetician had to adjust the current, depending on the thickness of your skin.

Now, NuSkin holds the patent on the only hand-held Galvanic Spa, which is roughly the size of a cell phone, that self-adjusts to your skin, so you can use it safely and easily in your own home at your convenience.

As we age, various internal sources age us and affect our bodies, making us lose some of our bodies’ abilities to function as they once did. These natural internal changes are manifested as symptoms of aging that we can see and feel.

Imagine if you could slow internal sources of aging?

Nu Skin recently discovered one internal aging source and how to slow its activity. But this is only 5% of where they will take this technology as Nu Skin scientists continue to unlock the secrets around the sources of aging that affect the way people look, feel, and live.

New research by Drs. James and Dorothy Morré has identified a major, previously undiscovered source of aging within each of us: arNOX—an enzyme that generates damaging free radicals—and our genes control its activity, which increases as we age. Present on the surface of our cells, this invisible enemy is capable of generating skin damaging free radicals around the clock that can destroy collagen and elastin. The result? Looking years older than you already are.

Scientists have discovered that for most people, arNOX activity starts to increase during the “aging” years, beginning sometime during the mid-thirties and exponentially increasing for the next few decades.

Studies have also shown that a person’s arNOX activity is not triggered by sun exposure, providing further evidence that increased arNOX activity is an identified source of internal aging.

Some of us have more of the arNOX enzyme and some have less. The results showed that those with more look an average of 7 years older and those with less, look on average 7 years younger.

If you’re the kind of person that values scientific research, then you’re going to love what both Purdue and Stanford University discovered when they conducted tests on ageLOC technology and the Galvanic current.

+7/ -7 Why Some of Us Look Younger—or Older—than We Are

BACKGROUND

Although the skin care industry has made some significant progress toward the correction and prevention of the visible signs of aging, there are still many unknown factors regarding why we age—and why we all seem to age differently.

The effects of the sun and the environment are fairly well understood and highly effective sunscreens exist to help us avoid the aggressive aging effects of ongoing exposure. Less understood are the biological or intrinsic processes that affect our appearance over time.

Recently, scientists at Purdue University in collaboration with Nu Skin Research and Development, have discovered a new and potentially significant internal source of aging—an enzyme called arNOX.

Present on the surface of our cells, this enzyme is capable of generating skin damaging free radicals in the epidermis around the clock.

Mostly inactive in our youth, activity levels of arNOX increase as we age and vary by individual. To learn more about how a person's arNOX activity levels might correlate to their real or perceived age, in 2006 Nu Skin collaborated on a research study with Purdue University and the Stanford School of Medicine. The results will be presented at the 25th International Federation of Societies of Cosmetic Chemists Congress to be held in Barcelona, Spain in October 2008.

STUDY TITLE

A Randomized Pilot Study of the Relationship between arNOX Levels and Appearance of Aging Skin Participants : 25 females, ages 45-65

METHODS

Using a VISIA complexion analysis machine, close-up images of the faces of twenty five women between 45 and 65 years of age were taken and analyzed. Assessments were made of key indicators of aging skin such as wrinkles, pore size, evenness of color, porphyrins, and UV spots. A panel of independent clinical skin graders reviewed the close-up photographs taken by the VISIA and estimated each participant’s chronological age based on the condition of their skin. The professional panel estimated ages were averaged for each subject, and then compared to subject’s actual age. The arNOX enzyme activity levels from each test subject were determined by drawing blood samples which were then processed and analyzed at Purdue University. Finally, researchers compared and correlated each participant's professionally estimated chronological skin age and real age with the arNOX activity levels in the blood.

RESULTS

According to preliminary data, a correlation exists between arNOX activity levels and errors in estimating participants' chronological skin ages as estimated by professional graders.

In other words, the apparent visible ages of those with higher arNOX activity levels were estimated to be an average of seven years older than their chronological age while the apparent visible ages of those individuals with lower arNOX activity levels were estimated to be an average of seven years younger than their chronological age.

This suggests that low activity levels of arNOX may result in looking visibly younger—as we get chronologically older.

Conclusion: The first half of the slide shows what your cells normally look like with the arNOX toxic enzyme in full force causing aging.

The second half of the slide, once the ageLOC techlology gel is applied with the Galvanic current, shows the arNOX toxic enzyme with no activity, literally halting the aging process in your cells. This stops the aging process in your cells for approximately 48 hours, so the treatment is done twice per week. It has a cumulative effect, so over time, it reverses the signs of aging.

NuSkin’s Galvanic Spa II comes with four different attachments that can be used with different products. The ageLOC technology gels are used on the face, neck and backs of hands. The Body Shaping Gel is used on stretch marks and cellulite on the stomach, legs and arms. The True Face Line Corrector is used on fine lines and wrinkles around the eyes and mouth, and the last attachment is used with the Nutriol product for your hair and scalp.

Along with the hand-held Galvanic Spa II and four head attachments, it comes with two boxes of the ageLOC Technology gels, for a one month supply, one tube of Body Shaping Gel, for your “grandma” arms, hands, stretch marks on your stomach and legs, a How-To-Use-the-Spa DVD, and a carrying case. This retails for $350. Replacement gels, $7 per treatment.

Spa Industry Facts:

145 Million spa visits in 2007 in the US*
Globally spas generate over $40 Billion in Revenue**
Average spa client spends $143/visit**
Similar spa treatments range from $100-$200
NuSkin ageLOC Galvanic Spa Face Treatment – $7


*Source – Dunn & Bradstreet – Int’l. Spa Assoc.
**Source – Forbes

Press Release:

Nu Skin Scientists Identify Additional Free Radical Generator May 14, 2008

Activity of Enzyme on Skin Cells Correlates with Age

KYOTO, Japan, May 14 /PRNewswire-FirstCall/ — New research funded by Nu Skin Enterprises on internal causes of aging has identified a previously unknown source of superoxide free radicals. Free radicals from external triggers, such as sun exposure and cigarette smoke, have long been known to damage skin cells and components of the skin’s extracellular matrix, including collagen and elastin.

Scientists from Nu Skin Enterprises and Purdue University report their novel research findings on age-related NADH oxidase (arNOX) this week in Kyoto, Japan, at International Investigative Dermatology 2008 (IID2008), a major scientific venue for the latest information on skin biology. The scientists present compelling evidence that arNOX, an enzyme associated with cell membranes, is present and active on skin cells. Significantly, arNOX activity increases during the “aging” years of about 45-70.

“Identifying skin-associated arNOX and its increasing activity with age is a breakthrough discovery in understanding skin aging,” said Zoe Diana Draelos, MD, primary investigator with Dermatology Consulting Services, member of the Nu Skin Scientific Advisory Board and one of the study authors. “Currently, most dermatological research focuses on correcting skin damage after it occurs. Identifying an internal source of free radicals in skin, and advancing an understanding of how and why they are generated, adds to our ability to address fundamental mechanisms that may combine with external sources to lead to accelerated skin aging.”

“Evidence of arNOX in the skin provides further insights into potentially revolutionary therapies for skin care, particularly because its activity correlates with the ages when people begin to see their skin lose its elasticity and firmness, and notice more discoloration and lines and wrinkles,” remarked Helen Knaggs, PhD, vice president of Nu Skin global research and development. “If we can develop innovative ways to inhibit arNOX activity and prevent the production of free radicals in the first place, then we can address both sides of the equation — correcting free radical damage from external sources, while at the same time preventing free radical production from internal sources.”

Authors of the study are Dale Kern, senior scientist for Nu Skin Enterprises; Dr. Draelos; Dorothy Morre, PhD, professor of foods and nutrition, Purdue University; and D. James Morre, PhD, Dow distinguished professor of medicinal chemistry, Purdue University. Nu Skin has funded ENOX research by the Morres since 1999.

About arNOX

The arNOX enzyme is one in a class of newly-identified ECTO-NOX (external NADH oxidase or ENOX) proteins that are located on external cell membranes. ECTO-NOX proteins become increasingly active to generate additional metabolic energy as cell mitochondria age and produce less energy. arNOX has been identified in all cells tested, including serum and saliva and now the dermis and epidermis. Its unique property is that it generates superoxide at the cell surface that is capable of damaging adjacent cells, lipoproteins, and other structural components of the skin’s extracellular matrix, such as collagen and elastin. Other NOX categories include tumor-NOX, viral-NOX and constitutive, or normal, NOX.

About IID2008

International Investigative Dermatology 2008 is the fifth joint meeting of the Society for Investigative Dermatology (SID), the European Society for Dermatological Research (ESDR) and the Japanese Society for Investigative Dermatology (JSID). IID2008 is hosted in Kyoto, Japan, May 14-17, and is the only major venue this year for the presentation of the latest information on skin biology and skin diseases. The conference program is widely based on any of the basic and clinical dermatological fields.

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Tru Face Essence Ultra

I wonder if you’ve realized that after age 25 our skin stops producing elastin, which promotes sagging and wrinkles as we age. With research showing that anything that is used on your skin after a Galvanic Spa treatment is 70% more effective, you’ll want to make sure you are using an effective product to combat aging. NuSkin offers the third product, in their “Triple Play” in the anti-aging arena. This product has been 17 years in the making and is the perfect complement to the Galvanic spa and ageLOC gels. It is used twice per day on a clean face and neck, before applying your daytime or nighttime moisturizer.

100% Money-Back Guarantee: If after using this product twice per day for 60 days, you feel that you don’t have the elastin levels of a 20-year old, the company will refund 100% of your money.

Imagine how incredible you’re going to look and feel once you start using this product!

Welcome to the future of anti-aging skin. It’s time to put the bounce back in your skin with Tru Face® Essence Ultra.

Featuring Ethocyn®

Ethocyn® patented anti-aging ingredient, clinically proved to improve skin’s elastin fiber content. Tru Face Essence Ultra is the ultimate anti-aging treatment product now with CoQ10 to promote cellular energy and a complete patent pending antioxidant network for younger looking skin today and tomorrow.

Benefits

• Promotes skin firmness and elasticity and fights current signs of aging with Ethyocyn®, an ingredient clinically proven to improve skin elastin content.
• Helps prevent degradation of elastin with elastase inhibitors.
• Contains Tégreen 97, CoQ10 and colorless carotenoids, a complete protective antioxidant network that helps prevent future signs of aging by protecting against skin-aging free radicals
• Helps contour and firm the skin for a more youthful appearance.
• Defines skin around the eyes, neck, chin, jawline and décolleté and hands.

If you’re the kind of person that likes to look your best all the time, then you’re going to love this product!

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P.S. - Buy your spa today and look younger than you have in years.